Lot MS431 Save $22.50 MOTS-C 10mg Research Peptide

Research peptide · Lyophilized

MOTS-C 10mg Research Peptide

MOTS-C — USA Made, ≥99% Purity

4.9 177 verified reviews

16-amino-acid mitochondrial-derived peptide in a 10mg vial
USA manufactured in GMP-certified California and Arizona laboratory facilities
≥99% purity target with third-party HPLC, mass spectrometry, and combined COA

$89.99 $112.49 Save $22.50

Manufactured in a GMP facility · Independently tested · Batch COA

Dispatched from a US warehouse within 48 hours, tracked

Certificate of analysis for lot MS431 below

Disclaimer

For research purposes only. Not intended for human consumption, medical use, diagnosis, treatment, or prevention of disease.

Specifications

Lot MS431

Purity target

≥99%

≥99% (3rd-Party HPLC Tested)

Molecular mass

2,174.6

g/mol, confirmed by mass spectrometry

Residues

Synthetic amino-acid chain

Sequence

Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (MRWQEMGYIFYPRKLR)

CAS: 1627580-64-6
Molecular mass: 2,174.6 g/mol
Purity target: ≥99% (3rd-Party HPLC Tested)
Form: Lyophilized Powder
Origin: Manufactured, Formulated & Packaged in CA/AZ, USA
Storage: Store at -20°C (Freeze) or 2–8°C (Refrigerated) protected from light

What is MOTS-C?

MOTS-C is a 16-amino-acid mitochondrial-derived peptide encoded by a short open reading frame within mitochondrial 12S rRNA. That origin makes it an unusual research target: it is part of the signaling conversation between mitochondria and the rest of the cell.

Researchers study MOTS-C in models of metabolic stress, nutrient sensing, and cellular adaptation. Much of the evidence is preclinical, and its broader roles across tissues remain an active area of investigation.

How It Works

Changes one-carbon metabolism: MOTS-C has been shown to interact with the folate-methionine cycle in experimental models.

Raises AICAR signaling: Those pathway changes can increase AICAR, a cellular indicator associated with low-energy conditions.

Activates AMPK: AICAR-linked AMPK activation helps researchers examine downstream energy-management and stress-response pathways.

Analytical data

Every lot, on the record

Independent third-party HPLC evaluates the purity target, while mass spectrometry confirms molecular identity. Both results are documented in one combined, batch-specific Certificate of Analysis.

Purity (HPLC-UV)

99.64%

Net content

10.59 mg

Reported

2026-06-01

Identity (LC-MS): Confirmed
Appearance: White Lyophilized Powder

HPLC MS

Analyte	Method	Result
Identity	LC-MS	MOTS-C
Purity	HPLC-UV	99.64%
Net Content		10.59 mg

Chromatogram

Mass confirmation

Download COA (PDF)

Why Source from 321 Peptides?

Domestic synthesis and finishing.

MOTS-C is manufactured in GMP-certified California and Arizona facilities, not sourced from overseas or Mexico. That keeps the chain of custody short and accountable.

Sequence confidence through two tests.

Third-party HPLC assesses the ≥99% purity target, while mass spectrometry checks the expected 16-residue identity. Results are combined into a lot-specific COA.

Lyophilized protection.

Freeze-drying supports peptide stability during cold storage and domestic transit. Fast U.S. fulfillment reduces unnecessary shipping exposure.

Lot history 4 released lots

Every batch released under this compound, with the figure reported for each.

Lot	Reported	Purity	Net content	COA
MS431	2026-06-01	99.64%	10.59 mg	PDF
MO-57344 Superseded	2026-05-06	99.46%	10.02 mg	Pending
MO-57921 Superseded	2026-05-02	99.58%	10.03 mg	Pending
MO-56767 Superseded	2026-04-08	99.49%	10.01 mg	Pending

Frequently Asked Questions

What is MOTS-C peptide?

MOTS-C is a 16-amino-acid peptide encoded by a short region of mitochondrial DNA. Researchers study it as a mitochondrial signaling molecule involved in metabolic-stress pathways.

How does MOTS-C work?

Preclinical research suggests MOTS-C alters folate-cycle and purine-synthesis activity, increasing AICAR and activating AMPK. These findings describe experimental mechanisms, not guaranteed human effects.