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Lot R1399 Save $27.50 Retatrutide Research Peptide
Research peptide · Lyophilized

Retatrutide Research Peptide

Retatrutide — USA Made, ≥99% Purity

4.9 177 verified reviews
  • 39-residue, lipidated triple-agonist research peptide in a 10mg vial
  • USA manufactured in GMP-certified California and Arizona laboratory facilities
  • ≥99% purity target with third-party HPLC, mass spectrometry, and batch COA
Vial Size

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Manufactured in a GMP facility · Independently tested · Batch COA
Dispatched from a US warehouse within 48 hours, tracked
Certificate of analysis for lot R1399 below
Disclaimer

For research purposes only. Not intended for human consumption, medical use, diagnosis, treatment, or prevention of disease.

Specifications

Lot R1399
Purity target
≥99%
≥99% (3rd-Party HPLC Tested)
Molecular mass
4,731.33
g/mol, confirmed by mass spectrometry
Vial content
10 MG
Lyophilized Powder
Sequence
Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-Lys(AEEA-γGlu-C20 diacid)-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS
2381089-83-2
Molecular mass
4,731.33 g/mol
Purity target
≥99% (3rd-Party HPLC Tested)
Form
Lyophilized Powder
Origin
Manufactured, Formulated & Packaged in CA/AZ, USA
Storage
Store at -20°C (Freeze) or 2–8°C (Refrigerated) protected from light

What is Retatrutide?

Retatrutide, also called LY3437943, is an investigational 39-amino-acid peptide with a fatty-diacid modification. It was engineered as a single molecule capable of activating GIP, GLP-1, and glucagon receptors in experimental systems.

Researchers study retatrutide to understand how three nutrient- and energy-signaling receptor pathways interact. It remains investigational and is not FDA approved for human use, so this material is positioned strictly for controlled non-clinical research.

How It Works

01

Activates GIP receptors: This pathway is studied for roles in nutrient-responsive signaling and metabolic regulation.

02

Activates GLP-1 receptors: Researchers examine downstream signaling related to glucose-dependent and energy-balance pathways.

03

Activates glucagon receptors: The third activity supports investigation of hepatic signaling, substrate use, and energy-expenditure mechanisms.

Analytical data

Every lot, on the record

Independent third-party HPLC evaluates the purity target, while mass spectrometry confirms molecular identity. Both results are documented in one combined, batch-specific Certificate of Analysis.

Retatrutide Research Peptide
Lot R1399 · Freedom Diagnostics Testing
VERIFIED
Purity (HPLC-UV)
99.79%
Net content
11.74 mg
Reported
2026-06-01
Identity (LC-MS)
Confirmed
Appearance
White Lyophilized Powder
HPLC MS
Analyte Method Specification Result Pass/fail
Identity LC-MS GLP RT
Purity HPLC-UV 99.79%
Net Content 11.74 mg
Chromatogram thumbnailChromatogram Chromatogram, full size
Mass confirmation thumbnailMass confirmation Mass confirmation, full size
Download COA (PDF)

Why Source from 321 Peptides?

Domestic control for a complex molecule.

Retatrutide is synthesized and finished in GMP-certified California and Arizona facilities, with no overseas or Mexico sourcing.

Identity verified beyond the name.

Third-party HPLC evaluates the ≥99% purity target and mass spectrometry checks the complex lipidated molecular identity. One combined COA reports both results for the batch.

Protected as a freeze-dried vial.

Lyophilization supports stability during storage and domestic transit. Rapid U.S. fulfillment shortens supply-chain exposure.

Lot history 8 released lots

Every batch released under this compound, with the figure reported for each.

Lot Reported Purity Net content COA
R1399 2026-06-01 99.79% 11.74 mg PDF
R1340 2026-06-01 99.87% 22.75 mg PDF
RE-72936 Superseded 2026-05-12 99.64% 20.06 mg Pending
RE-73513 Superseded 2026-04-30 99.88% 20.08 mg Pending
RE-43145 Superseded 2026-04-23 99.46% 10.02 mg Pending
RE-44299 Superseded 2026-04-08 99.83% 10.04 mg Pending
RE-43722 Superseded 2026-03-19 99.58% 10.03 mg Pending
RE-74090 Superseded 2026-02-25 99.71% 20.10 mg Pending

Frequently Asked Questions

What is Retatrutide?

Retatrutide is an investigational lipidated peptide designed to activate GIP, GLP-1, and glucagon receptors. It is also known by the development code LY3437943.

How does Retatrutide work?

Retatrutide activates three receptor systems involved in nutrient and energy signaling: GIPR, GLP-1R, and GCGR. Researchers study the combined pathway response rather than a single-receptor effect.

Is Retatrutide FDA approved?

No, retatrutide is investigational and is not FDA approved for human use. This 10mg vial is supplied only for non-clinical research.

Which COA applies to my vial?

The lot code printed on the vial. Select it above and the certificate for that batch is returned, including the chromatogram it came from.